Scientists at the 石榴视频黄色版 have identified the first cases of the Omicron variant in the state. Julie Hirschhorn, Ph.D., directs the molecular pathology lab that found them. 鈥淚t is three cases, all of them in the Lowcountry. Two out of the three were fully vaccinated, but not boosted. And one had only one dose of the vaccine.鈥�

One is in Charleston, another in North Charleston and the third on Johns Island.听

Hirschhorn鈥檚 lab sequences all COVID cases that come through MUSC for testing. Sequencing involves looking at the virus鈥檚 genome to check for variants. The scientists sequence in batches they call runs.

鈥淪ince the identification of Omicron in Africa, we've been trying to do a run each week to make sure that we're sequencing as real time as possible. The more real time you do sequencing, the better handle you have on what's going on in the population,鈥� she said.

The first Omicron case in South Carolina involved a COVID sample collected for testing on Dec. 4. That means the fast-spreading variant has been here for at least a couple of weeks.

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Based on Omicron鈥檚 track record elsewhere, the numbers could rise quickly. 鈥淲hen a new variant is identified, the first thing that we can really get a good handle on is transmission, because we watch the number of cases and how quickly that increases. And Omicron is pretty prevalent right now over in the U.K. The U.K. seems to be doubling Omicron cases about every day,鈥� Hirschhorn said.

鈥淪o it does seem to be more transmissible than Delta. There's not a whole lot of evidence about severity of disease yet, because we're just starting to see the hospitalizations. In Australia, hospitalizations are pretty low. The hospitalizations in the U.K. also appear to, in early terms, suggest that it's maybe more mild disease. That鈥檚 great, except that if you have COVID circulating in large quantities, then you always have that ability for more mutations to happen. And so I think it's pretty critical that people try and protect themselves in any way that they can.鈥�

She encouraged people to get booster shots.听鈥�All three of our Omicron cases were in people at least six months out from their latest shot. The data supports that if you're six months out, you should probably get boosted,鈥� Hirschhorn said.

Her team will continue to look for Omicron and keep the public informed about its findings. 鈥淣ow, for our lab, the most important thing is to continue sequencing to look at our transmission rate in South Carolina. We've been very fortunate with the听听dollars and the support from the state to do consistent testing across the state and surveillance,鈥� she said.

鈥淎nd so, because the state has supported us, we really feel the need to support the state back. Being one of the leading medical centers in South Carolina, it's very important to us that we inform our population; that we stay on top of their health and any issues that might arise. And so I plan on continuing to sequence as much, and as often as we can, because I do feel like this knowledge really empowers people to make decisions that will impact them.鈥�

The molecular pathology team at MUSC has played a leading role in providing that kind of knowledge since the early days of the pandemic. When the coronavirus arrived, the lab听quickly ramped up for COVID testing, working with sites across the state. It began sequencing for variants听last spring听and sharing its findings with the public. Along the way, it identified听mutations of the Delta variant, including one so prevalent that it may get its own name.

Now, as we head into the winter holidays, COVID cases are on the rise in South Carolina. Most involve the Delta variant. While knowing which variants are circulating is important because it tells us how the virus is changing and spreading, Hirschhorn said it鈥檚 less valuable for individuals to know which variant they were infected with because it won鈥檛 change the treatment they get. COVID is COVID. And it鈥檚 still here as we head into another holiday season.

鈥淚 encourage people to consider risk stratification going into the holiday season and just being cognizant of what you want to do and finding a way to do it that's safer,鈥� Hirschhorn said.